期刊文献+

Salusins在动脉粥样硬化发生中的作用的研究进展 被引量:3

暂未订购
导出
摘要 Salusins是Shiehiri等[1]利用生物信息学的分析方法,于2003年从已经完成的人类基因组计划的基因文库中,筛选出来的新的血管活性肽,包含28个氨基酸残基组成的salusin-α和20个氨基酸残基组成的salusin-β。Salusins作为新的血管活性肽,具有降低血压、减慢心率[1]、促进心肌肥大[2]等作用,特别是在动脉粥样硬化性疾病(atherosclerosis,AS)研究领域中成为热点[3]。salusin-α和salusin-β在AS的发生发展中具有相反的作用,有望成为AS治疗的新靶点。
作者 杨超君 杨俊
出处 《实用医学杂志》 CAS 北大核心 2014年第10期1663-1665,共3页 The Journal of Practical Medicine
基金 国家自然科学基金(编号:81170133 81200088) 宜昌市科技研究与开发项目(编号:A12301-01)
  • 相关文献

参考文献2

二级参考文献9

共引文献8

同被引文献34

  • 1DOHI T, MIYAUCHI K,OKAZAKI S, et al. Plaque regressiondetermined by intravascular ultrasound predicts long-termoutcomes of patients with acute coronary syndrome [J]. JAtheroscler Thromb,2011,18(3) :231-239.
  • 2STONE GW, MAEHARA A, LANSKY AJ, et al. A prospectivenatural-history study of Coronary atherosclerosis [J]. N Engl JMed, 2011,364(3):226-235.
  • 3SAHIN I,AYDIN S. Serum concentration and kidney expressionof salusin-alpha and salusin-beta in rats with metabolic syndromeinduced by fructose [J]. Biotech Histochem, 2013 ,88 (3-4):153-160.
  • 4TI Y, WANG F, WANG ZH, et al. Associations of serumsalusin-alpha levels with atherosclerosis and left ventriculardiastolic dysfunction in essential hypertension [J]. J HumHypertens, 2012,26(10):603-609.
  • 5WATANABE T,SATO K, ITOH F, et al. Emerging roles forvasoactive peptides in diagnostic and therapeutic strategiesagainst atherosclerotic cardiovascular diseases [J]. Cun ProteinPeptSci, 2013,14(6):472-480.
  • 6NAGASHIMA M, WATANABE T,SHIHA1SHI Y, et al.Chronic infusion of salusin-alpha and -beta exerts oppositeeffects on atherosclerotic lesion development in apolipoprotein E-deficient mice [J]. Atherosclerosis, 2010,212( 1) :70-77.
  • 7WATANABE T,NISHIO K,KANOME T, et al. Impact ofsalusin-alpha and -beta on human macrophage foam cellformation and coronary atherosclerosis [J]. Circulation, 2008,117(5):638-648.
  • 8MCEVER RP. Adhesive interactions of leukocytes, platelets,and the vessel wall during hemostasis and inflammation [J].Thromb Haemost, 2001,86(3) :746-756.
  • 9CATAPANO AL, CHAPMAN MJ, DE BACKER G, et al.Comment to the position paper on global recommendations for themanagement of dyslipidemia developed by theInternational Atherosclerosis Society (IAS ) [J]. Atherosclerosis,2014,233(2):508-509.
  • 10刘军妮,徐冬玲,杜贻萌,蒋卫东,王欣,董兆强,陈良,胡晓波,王光允,许复郁,赵敬杰,郝琳,王群,鹿庆华.脂蛋白相关磷脂酶A_2与兔易损斑块的相关性研究[J].中国病理生理杂志,2010,26(4):669-675. 被引量:14

引证文献3

二级引证文献20

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部