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运动性与病理性心脏肥大 被引量：5

Exercise-induced and Pathological Cardiac Hypertrophy
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摘要 各种疾病造成心肌重塑和心脏肥大,最终发展为心力衰竭。相反,运动员的心脏同样也发生重塑与肥大,则属于生理性适应。对运动性和病理性心脏肥大的形态、功能、信号转导机制和影响因素等方面作一综述,以期为鉴别诊断、预防过度训练引起的心肌损伤甚至运动性猝死,以及为心血管疾病和心衰患者制定新的治疗策略提供借鉴与参考。 Various diseases can lead to myocardial remodeling and cardiac hypertrophy, eventually resulting in heart failure. In contrast, athletes are likely to have cardiac remodeling and hypertrophy during long-term exercise training, which was considered to be a physiological adaptation. The present review involved morphology, function, signal transduction and influential factor of exercise-induced cardiac hypertrophy and pathological cardiac hypertrophy to provide references for differential diagnosis ,prevention of exercise-induced myocardial injury and sudden death as well as new therapeutic strategies to treat cardiovascular diseases and heart failure patients.
作者 刘冠楠 陈钢
机构地区 东北师范大学体育学院 沈阳师范大学体育学院
出处 《沈阳体育学院学报》 CSSCI 北大核心 2014年第2期90-96,共7页 Journal of Shenyang Sport University
关键词 心脏重塑 运动性心脏肥大 病理性心脏肥大 心力衰竭 信号转导 cardiac remodeling exercise-induced cardiac hypertrophy pathological cardiac hypertrophy heart failure signal transduction
分类号 G804.54 [文化科学—运动人体科学]
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参考文献85

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二级参考文献81

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共引文献35

同被引文献55

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引证文献5

二级引证文献20

沈阳体育学院学报
2014年 第2期

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