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甲状腺功能亢进症伴严重药物性胆汁郁积性肝炎1例并文献复习 被引量:4

One case of hyperthyroidism with severe drug-induced cholestasis hepatitis and literature review
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摘要 甲状腺功能亢进症(甲亢)本身可导致肝功能损害,而抗甲状腺药物亦可引起肝功能损伤.但出现严重药物性胆汁郁积性肝炎的病例比较少见,临床治疗较为困难.本院收治1例,在治疗甲亢的基础上,采用甲强龙静脉脉冲冲击联合口服强的松的方案,降低患者胆红素水平,使肝功能恢复正常,甲亢亦得以控制. Hyperthyroidism can cause liver damage,while anti-thyroid drugs can also cause liver dysfunction. Severe case of drug-induced cholestasis hepatitis is rare, difficult to treat. Here we report a case with drug-induced cholestasis hepatitis. On the basis of the treatment of hyperthyroidism, intravenous methyl- prednisolone pulse therapy combined with oral prednisone was used to reduce bilirubin levels in patients, the- refore the liver function of the patient returned back to normal, and the hyperthyroidism was controlled.
出处 《国际内分泌代谢杂志》 北大核心 2014年第3期214-216,共3页 International Journal of Endocrinology and Metabolism
关键词 甲状腺功能亢进症 药物性胆汁郁积性肝炎 糖皮质激素 Hyperthyroidism Drug-induced cholestasis hepatitis Glucocorticoids
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参考文献9

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二级参考文献8

  • 1施秉银.甲状腺功能亢进症伴抗甲状腺药物所致肝损伤的识别与处理[J].中国实用内科杂志,2006,26(5):654-656. 被引量:27
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