摘要
血清胱抑素C是一种半胱氨酸蛋白酶抑制剂,由机体所有有核细胞以恒定的速率产生,其相对分子质量小,可被肾小球自由滤过,在近端肾小管被代谢.血清胱抑素C作为一种内源性标志物,可以较早的反映肾小球滤过率的变化,故其在糖尿病肾病早期诊断中有重要的价值.
Cystatin C, a cysteine proteinase inhibitor, is produced at a constant rate by nucleated cells, and is freely filtered by the renal glomeruli, metabolized by the proximal tubule.As an endogenous serum markers, cystatin C can reflect the early changes of glomerular filtration rate, so it has important value in early diagnosis of diabetic nephropathy.
出处
《国际内分泌代谢杂志》
北大核心
2014年第3期207-210,共4页
International Journal of Endocrinology and Metabolism
关键词
胱抑素C
糖尿病肾病
肾小球滤过率
Cystatin C
Diabetic nephropathy
Glomerular filtration rate
