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不同程度阻塞性睡眠呼吸暂停综合征病人颈动脉结构和功能的变化 被引量:2

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摘要 目的探讨不同程度阻塞性睡眠呼吸暂停综合征(OSAS)病人颈动脉结构和功能的变化。方法根据呼吸暂停低通气指数(AHI)将98例疑为OSAS的病人分为对照组(AHI<5次/h)、OSAS轻度(5次/h^20次/h)、中度(20次/h^40次/h)、重度(>40次/h)4组,记录所有病人的年龄、性别、身高、体重、血脂、血糖等指标,应用超声内中膜厚度定量分析(QIMT)和血管弹性定量分析(QAS)技术对其双侧颈动脉进行检查,评价其结构和功能。结果 OSAS重度组吸烟率高于其他各组,与对照组相比,OSAS重度组三酰甘油(TG)水平升高,与OSAS轻度组相比,OSAS重度组TG水平升高,差异有统计学意义(P<0.05)。4组间比较,内中膜厚度(IMT)、血管内径(D)、斑块无明显变化(P>0.05);与对照组比较,OSAS中度组脉搏波传导速度(PWV)、僵硬度指标(β)增大,差异有统计学意义(P<0.05);与轻度组相比,中度组PWV、β增大,与中度组相比,OSAS重度组β增大,差异有统计学意义(P<0.05)。结论超声能早期评价OSAS病人颈动脉结构和功能的变化,OSAS病人颈动脉弹性改变较结构改变早发生。
出处 《中西医结合心脑血管病杂志》 2014年第4期458-459,共2页 Chinese Journal of Integrative Medicine on Cardio-Cerebrovascular Disease
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参考文献10

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