摘要
艾纳香为我国华南地区的特色地道药材,黄酮类成分是其主要活性成分之一。随着仪器分析技术的进步,现已经从艾纳香中分离出了艾纳香素、槲皮素、鼠李素、柽柳黄素、木犀草素、木犀草素-7-甲醚等黄酮类、黄酮醇类、二氢黄酮类、二氢黄酮醇类、查尔酮类等黄酮化合物20余种。药理学研究表明,其具有抗肿瘤、保肝护肝、抗氧化、抗酪氨酸激酶等生物活性。本文主要对艾纳香的黄酮类化学成分和药理活性进行综述,以期为艾纳香中黄酮类化合物的综合开发与利用提供参考。
Blumea balsamifera DC. is a traditional herb widely used in south China, and flavonoids have been found to be the main active ingredient of this herb. With the progress of instrumental analysis technology, a series of flavonoids were isolated from this herb such as blumeatin,quereetin, rhamnetin,tamarixetin, luteolin, luteolin-7-Methyl ether, etc. Flavonoids similar to flavonol, flavanone, dihydro-flavonol, ehalcone also were isolated from different extracts or different tissues. Recent studies found that those flavonoids have antitumor, antioxidant,anti-tyrosine kinase activity and liver protection. In this paper, the chemical composition and pharmacological activity of flavonoids are summarized, which provides an evidence for its comprehensive development and utilization.
出处
《广东药学院学报》
CAS
2014年第1期123-126,F0003,共5页
Academic Journal of Guangdong College of Pharmacy
基金
国家自然科学基金(81374065)
海南省社会发展科技专项资金项目(2012sf015)
关键词
艾纳香
黄酮
生物活性
艾纳香素
开发与利用
Blumea balsanifera DC.
flavonoid
bioactivity
blumeatin
development and utilization
