摘要
目的探讨小剂量奥美拉唑治疗功能性消化不良(FD)的临床疗效。方法选择中山市南朗医院收治的FD患者160例,将其分为研究组与对照组,每组80例。研究组给予口服小剂量的奥美拉唑进行治疗,对照组给予口服多潘立酮联合埃索美拉唑进行治疗。结果两组症状改善情况及治疗效果比较差异无统计学意义(P均>0.05);研究组不良反应发生率明显低于对照组(P<0.05)。结论小剂量奥美拉唑治疗FD效果显著,具有见效快、不良反应少、症状改善明显等优势,安全可靠,值得大力推广,应用于临床。
Objective To investigate the clinical effect of low-dose omeprazole on functional dyspepsia （FD）. Methods The 160 patients with FD in Nanlang hospital of Zhongshan were divided into study group and control group, with 80 cases in each group. Low-dose of omeprazole was orally given in study group, and domperidone combined with esomeprazole was orally given in control group. Results There were no significant differences in the improvement of symptoms or treatment effect between the two groups （ all P 〉 0. 05 ）. The incidence of adverse events was significantly lower in study group than that in control group（P 〈 0.05）. Conclusion Low-dose omeprazole has good effect on FD, has the advantages of instant effect, less adverse reactions, symptoms improved significantly, and is safe and reliable, it is worthy promoting for clinical application.
出处
《临床医学》
CAS
2014年第4期12-13,共2页
Clinical Medicine
