摘要
目的了解抗菌药物对多重耐药鲍曼不动杆菌的体外抗菌活性。方法对某院2013年1—5月临床各科室送检标本分离的224株多重耐药鲍曼不动杆菌进行鉴定及药敏试验。结果 224株多重耐药鲍曼不动杆菌主要分布在呼吸内科(21.43%),其次是脑外科(16.07%)、脑外重症监护室(ICU,12.50%)和神经内科(12.50%)等。标本来源以痰液(57.14%)为主,其次是气管插管(16.52%)和引流液(9.82%)等。多重耐药鲍曼不动杆菌对替加环素敏感,对米诺环素耐药率为7.14%,对其余8种抗菌药物的耐药率均≥75%,其中头孢替坦耐药率高达98.21%。结论替加环素对该院多重耐药鲍曼不动杆菌具有良好的抗菌效果。
Objective To evaluate in vitro activity of antimicrobial agents against multidrug-resistant Acinetobacter baumannii （MDR A. baumannii）. Methods 224 MDR A. baumannii strains isolated from specimens of clinical de- partments in a hospital between January and May 2013 were identified and performed antimicrobial susceptibility tes- ting. Results 224 MDR A. baumannii strains were mainly isolated from respiratory disease department（21.43 % ）, neurosurgical department （16. 07%）, neurosurgieal intensive care unit （12. 50%）, and neurology department （12. 50%）. The major specimens of A. baumannii was sputum （57. 14%）, the next were tracheal intubation （16.52%） and drainage fluid（9. 82%）. MDR A. baumannii strains were sensitive to tigecycline, the resistant rate to minocycline was 7. 14%,to the other eight antimicrobial agents were all ≥75%, resistant rate to cefotetan was up to 98. 21%. Conclusion Tigecycline is highly effective against MDR A. baumannii in this hospital.
出处
《中国感染控制杂志》
CAS
2014年第3期138-140,共3页
Chinese Journal of Infection Control
关键词
多重耐药鲍曼不动杆菌
抗菌药物
抗药性
微生物
医院感染
multidrug-resistant A. baumannii
antimicrobial agent
drug resistance, microbial
healthcare-associ ated infection
