摘要
目的观察红花黄色素注射液治疗AECOPD合并慢性肺源性心脏病患者的疗效。方法选择本院确诊为AECOPD合并慢性肺源性心脏病患者69例,随机分为治疗组35例,在常规西药治疗基础上加用红花黄色素注射液150 mg静脉滴注,1次/d,共14 d。对照组34例采用西药基础常规治疗,用药前后对临床症状改善,血气指标,血液流变学指标,肺通气功能及心功能NT-proBNP指标进行对比观察。结果治疗组患者较对照组,治疗前后临床症状改善,血流变指标改善,肺功能FEV1、FEV1/FVC×100%、FEV1%,心功能NT-proBNP相关实验室指标均有明显改善(P<0.05)。结论中西医结合在AECOPD合并慢性肺源性心脏病常规治疗基础上加用红花黄色素注射液对患者临床症状改善,血液粘稠度,血液流变学,肺功能及心功能改善明显,临床疗效确切。
Objective To observe the curative effect of safflower yellow pigment injection in the treatment of AECOPD patients complicated with chronic pulmonary heart disease （CPHD）. Methods 69 AECOPD patients complicated with CPHD were randomly divided into the treatment group （n = 35 ） and the control group （n = 34）. All patients were given conventional treatment of western medicine, and the treatment group was additionally treated with safflower yellow pigment injection 150 mg intravenous drip, once per day for 14 days. The clinical symptoms, blood gas index, hemorheology indexes, pulmonary ventilation function and cardiac function were compared. Results The improvement of clinical symptoms, lung function, and cardiac function was more pronounced in the treatment group than in the control group （ P 〈 0. 05 ）. Conclusion Safflower yellow pigment injection combined with western medi- cine can improve their clinical symptoms, blood viscosity, blood rheology, pulmonary function and cardiac function significantly in the treatment of AECOPD patients complicated with CPHD.
出处
《临床肺科杂志》
2014年第6期1039-1041,共3页
Journal of Clinical Pulmonary Medicine
关键词
AECOPD合并慢性肺源性心脏病
中西医结合
红花黄色素注射液
临床疗效
AECOPD patients complicated with chronic pulmonary heart disease
integrated traditional Chi-nese and western medicine
safflower yellow injection
clinical effect
