摘要
目的:探讨胺碘酮联合美托洛尔治疗心力衰竭的临床疗效。方法选取2012年10月-2013年10月本院收治的心力衰竭患者160例,将其随机分为观察组和对照组各80例,对照组给予胺碘酮治疗,观察组在对照组治疗的基础上加用美托洛尔,观察两组患者的心功能改善情况,并进行疗效评定。结果观察组总有效率为98.75%,显著高于对照组的85.00%,差异有统计学意义(P〈0.05)。两组治疗后SBP、DBP、HR、LVEDD、LVESD及LVEF均较治疗前改善,且治疗后观察组上述指标均优于对照组(P〈0.05)。结论胺碘酮联合美托洛尔治疗心力衰竭疗效显著,心功能改善明显,值得临床推广应用。
Objective To evaluate the clinical efficacy of amiodarone combined with metoprolol in the treatment of heart failure. Methods Our hospital from October 2012 to October 2013 were treated with heart failure in 160 patients, randomly divided into into combined treatment group of 80 patients and a control group of 80 patients in the control group with amiodarone, combination therapy group received treatment based on the combination of metoprolol treatment. Results The two groups of patients treated control group improved heart function after total effective rate was 98.7%, the combined treatment group was 85.00%. The difference was significant (P〈0.05). Conclusion The combined amiodarone and metoprolol treatment of heart failure has good clinical efficacy in improve cardiac function is superior to amiodarone alone group.It is worthy of clinical application.
出处
《中国实用医药》
2014年第8期26-27,共2页
China Practical Medicine
基金
河南大学校内科研基金一般项目(项目编号:2010 YBZR021)