摘要
目的分析无脑缺血症状的高血压患者颅内外动脉粥样硬化病变的发生频率及分布特征,并探讨其危险因素。方法对106例无脑缺血症状的高血压患者采用经颅多普勒超声(Transcranial Doppler,TCD)和颈动脉超声判断颅内外动脉粥样硬化病变,分析各危险因素的影响。结果 69例有颅内外动脉粥样硬化病变,其中23例颅内动脉狭窄,2例颅外颈动脉狭窄或闭塞。颅内动脉狭窄发生率明显高于颅外颈动脉狭窄或闭塞(P<0.05)。Logistic多元回归分析显示与年龄、高血压病病程及高脂血症相关。结论无脑缺血症状的高血压病患者,半数以上存在颅内外动脉粥样硬化病变,年龄、高血压病病程和高脂血症是颅内外动脉粥样硬化病变的独立危险因素。
Objective To detect the distribution of cervicocerebral atherosclerosis and evaluate its risk factors in asymptomatic patients with hypertension. Methods A total of 106 patients with hypertension but without cerebral ischemic stroke and ischemic attack were enrolled. All patients were examined with TCD and carotid duplex ultrasound. Results 69 cases were found with eervicocerebral atherosclerosis out of 106 patients. Intractmial cerebral stenosis was found in 23 patients. Incidence of intracranial cerebral stenosis （23/106） was higher than extracranial carptid artery stenosis or occlusion （2/106）. Multivariate logistic regression analysis showed that age ,duration of hypertension and hyperlipoidemia were independent factors significantly associated with cervicocerehral atherosclerosis. Conclusions Intracranial and extracranial atherosclerosis are detectable in more than half of the asymptomatic hypertension patients. Age, duration of hypertension and hyperlipoidemia are significant risk factors developing cervicocerebral atherosclerosis.
出处
《中风与神经疾病杂志》
CAS
CSCD
北大核心
2014年第4期345-347,共3页
Journal of Apoplexy and Nervous Diseases
基金
绍兴市2011年科技计划项目(No.2011D10025)
关键词
颅内动脉硬化
颈动脉疾病
高血压病
超声检查
Intracranial atherosclerosis
Carotid artery disease
Hypertension
Ultrasonography
