摘要
淋巴管内皮细胞特异性标志物的出现使淋巴管生成及淋巴管转移的分子机制成为肿瘤转移的研究热点。以往认为结肠癌肝转移的途径主要通过血道途径,而近期一些研究表明,淋巴管生成及淋巴结转移可能在结直肠癌肝转移的过程中同样发挥着至关重要的作用。笔者就淋巴管生成及其内皮特异性标志物在结直肠肝转移中的作用机制作一综述。
Lymphangiogenesis and mechanisms of lymphatic metastasis have become the research focus of tumor metastasis with the findings of the specific markers of lymphatic endothelium. Hematogenous metastasis has been thought previously to be the common route for colorectal cancer liver metastasis, but some recent research suggests that lymphangiogenesis and lymph node metastasis play an equally pivotal role in colorectal cancer liver metastasis. In this paper, the authors address the mechanisms of action oflymphangiogenesis and lymphatic endothelial-specific markers in colorectal cancer liver metastasis.
出处
《中国普通外科杂志》
CAS
CSCD
北大核心
2014年第4期517-520,共4页
China Journal of General Surgery
基金
山东省医学科学院院级科技计划青年基金资助项目(2013-45)
