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ELISA检测HIV感染者尿液标本中抗HIV-1抗体结果分析 被引量:9

Test of Anti - HIV - 1 Antibody in Urine Sample with ELISA
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摘要 目的 利用尿液标本检测抗HIV-1抗体。方法 通过ELISA方法检测50例抗HIV-1抗体阳性感染者及100例抗HIV-1抗体阴性对照组尿液中抗HIV-1抗体。结果 显示在50例HIV感染者中有49例尿液抗HIV-1抗体阳性,1例阴性;对照组中尿液中均未检测出抗 HIV-1抗体,以血液标本为标准,检测尿液抗 HIV-1抗体的灵敏性为 98.0%,特异性为 100%。尿液标本与血液标本检测的一致性达 99.3%。结论 本实验提示在采集血液标本不便的情况下,可通过尿液抗 HIV-1抗体的检测对高危人群的HIV感染情况进行监测和筛查。 Objective To test the anti - HIV - 1 antibody in urine sample. Methods Anti - HIV - 1 antibody had been tested in the urine samples from 50 HIV- 1 positive individuals and 100 HIV- 1 negative ones as a control by ELISA. Results Of 50 urine specimens from HIV - 1 positive individuals, 49 ones showed anti - HIV - 1 antibody positive and the left one negative. None of 100 urine specimens as a control showed anti - HIV - 1 antibody positive. Taking the results of the counterpart serum samples tested as standard, the sensitivity of the urine specimen HIV - 1 test kit was 98 % and, the specificity of it 100 % . Conclusion The results indicate that urine samples can be used to be screened for HIV - 1 antibody amongst the populations with high risk behavior in HIV-1 epidemic area if taking serum sample is unavailable.
出处 《中国性病艾滋病防治》 2001年第1期32-34,共3页 Chinese Journal of Std & Aids Prevention and Control
关键词 抗HIV-1抗体 尿液标本 筛查 艾滋病 ELISA HIV - 1 antibody Urine specimen Screen
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参考文献2

  • 1Cao Y,Friedman - Kien AE,Chuba J,et al.IgG antiboies to human immunodeficiency virus type 1 (HIV - 1 ) in the urine of HIV - 1 seropositive individuals[].The Lancet.1988
  • 2Cao Y,Hosein B,Borkowsky W,et aJ.Antibodies to human immunodeficiency virus type 1 in the urine specimens of HIV - 1 seropositive individuals[].AIDS Research and Human Retroviruses.1989

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