摘要
目的 探讨长疗程体外反搏及短疗程体外反搏对稳定型心绞痛的疗效及炎症因子的影响.方法 将90例稳定型心绞痛患者随机分为Ⅰ组（常规治疗组）、Ⅱ组（短疗程反搏组）及Ⅲ组（长疗程反搏组）,每组30例.Ⅰ组接受常规治疗,Ⅱ组接受常规治疗及15 d体外反搏治疗,Ⅲ组接受常规治疗及35 d体外反搏治疗.治疗35 d后对三组的治疗效果进行评价,用免疫比浊法测定治疗前后血中CRP水平.结果 Ⅰ组有效率55.2％,Ⅱ组有效率90.0％,Ⅲ组有效率93.1％.Ⅰ组治疗前后对比,CRP水平无明显变化;与治疗前对比,Ⅱ组、Ⅲ组治疗后CRP水平明显下降,且差异有统计学意义（P＜0.05）,但两组组间比较差异无统计学意义（P＞0.05）.结论 长疗程体外反搏与短疗程体外反搏在治疗稳定型心绞痛方面疗效相近,均优于单药治疗.
Objective To evaluate the effects of enhanced external counter-pulsation on inflammation factors in patients with chronic stable angina.Methods 90 patients with chronic stable angina were randomly assigned into 3 groups：Control group （group Ⅰ,n =30）,the short-term treatment group by enhanced external counter-pulsation with 15 d（group Ⅱ,n=30）,the long-term treatment group by enhanced external counter-pulsation with 35 d（group Ⅲ,n=30）.Evaluation of the clinical efficacy were conducted after the treatment.Immunoturbidimetric assays were applied to measure the level of CRP in sera collected from all the patients before and after the treatment.Results The effective rates of Group Ⅰ,Ⅱ,Ⅲ were 55.2％,90.0％,93.1％,respectively.In Group Ⅰ,there were no significant difference in the level of CRP,in Group Ⅱ and Ⅲ,there were significant difference in the level of CRP before and after treatment,but there were no significant difference between Group Ⅱ and Ⅲ.Conclusion There were no difference in treating chronic stable angina between short-term and longterm enhanced external counter-pulsation,which were superior to drug therapy.
出处
《中国心血管病研究》
CAS
2014年第4期296-299,共4页
Chinese Journal of Cardiovascular Research
关键词
体外反搏
冠状动脉疾病
炎症因子
C反应蛋白
Enhanced external counter-pulsation
Coronary heart disease
Inflammatory factor
CRP
