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子宫内膜双极多探针射频消融的有限元分析 被引量:6

Finite-element analysis of multiple electrode bipolar radio-frequency for global endometrial ablation
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摘要 目的运用有限元方法模拟子宫内膜射频消融过程中的温度场分布,为提高子宫内膜射频消融术的安全性和治疗效果提供理论依据。方法以三种常见大小的子宫腔为研究对象,根据生物热方程建立了子宫内膜的射频消融有限元模型,分析射频消融过程中靶向组织的最高温度、最低温度的变化,以及损伤面积和深度随子宫大小和射频电压(功率)不同产生的变化。结果电压不变、子宫尺寸变大时,最高温度变化较小,最低温度变小,损伤面增加但深度减小。子宫腔尺寸不变,功率变大时,最高温度增大,最低温度变化较小,损伤面积增加,深度增大。结论子宫内膜射频消融手术中同时考虑子宫腔大小和射频电压具有临床参考价值。 Objective To simulate the temperature distribution of multiple electrode bipolar radio- frequency(RF) for global endometrial ablation by finite element method. This thermotherapy might improve the safety and effectiveness of endometrial ablation. Methods With three common sizes of uterine cavity as the research objects and according to the bio-heat transfer equation,three finite element models were established to analyze the changes of peak temperatures, lesion area and lesion depth in different sizes of uterine cavity under different radio-frequency voltages. Results Under the same voltage, as the size of uterine cavity became greater, maximum temperature changed small, minimum temperature and lesion depth became lower, and lesion area was larger. In the same size of uterine cavity, as the power became higher, maximum temperature was higher, and minimum changed small, lesion region was larger and lesion depth was deeper. Conclusions Uterine cavity size and radio-frequency voltage should be considered in endometrial ablation.
作者 胡涛 肖家华
出处 《北京生物医学工程》 2014年第2期111-116,共6页 Beijing Biomedical Engineering
关键词 射频消融 异常子宫出血 子宫内膜消融 有限元分析 生物传热方程 radio-frequency ablation abnormal uterine bleeding endometrial ablation finite elementanalysis bio-heat transfer equation
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参考文献17

  • 1Senarclens MD.Book review:patterns and perceptions of menstruation[J].Journal of Biosocial Science,1984,16 (4):541-542.
  • 2Yin G,Li J,Zhu T,et al.Curative effects of two new endometrial ablation procedures using radiofrequency thermocoagulation for the treatment of severe abnormal uterine bleeding[J].Cell Biochemistry and Biophysics,2013:1-7.
  • 3Bourdrez P,Bongers MY,Mol BWJ.Treatment of dysfunctional uterine bleeding:patient preferences for endometrial ablation,a levonorgestrel-releasing intrauterine device,or hysterectomy[J].Fertility and Sterility,2004,82(1):160-166.
  • 4Lethaby A,Hickey M,Garry R,et al.Endometrial resection/ ablation techniques for heavy menstrual bleeding (review)[J].Cochrane Database Syst Rev,2009,4(1):CD001501.
  • 5Arturson G,Jakobsson OP.Oedema measurements in a standard burn model[J].Burns,1985,12 (1):1-7.
  • 6Tungjitkusolmun S,Staelin ST,Haemmerich D,et al.Three dimensional finite-element analyses for radio-frequency hepatic tumor ablation[J].Biomedical Engineering,IEEE Transactions on,2002,49(1):3-9.
  • 7Chang I.Finite element analysis of hepatic radiofrequency ablation probes using temperature-dependent electrical conductivity[J].Biomedical engineering online,2003,2 (1):12.
  • 8Haemmerich D,Tungjitkusolmun S,Staelin ST,et al.Finiteelement analysis of hepatic multiple probe radio-frequency ablation[J].Biomedical Engineering,IEEE Transactions on,2002,49 (8):836-842.
  • 9Ni Y,Mulier S,Miao Y,et al.A review of the general aspects of radiofrequency ablation[J].Abdominal Imaging,2005,30 (4):381-400.
  • 10Baldwin SA,Pelman A,Bert JL.A heat transfer model of thermal balloon endometrial ablation[J].Annals of Biomedical Engineering,2001,29 (11):1009-1018.

二级参考文献16

  • 1范晓筠,白景峰,陈亚珠.单针水冷式射频消融过程中组织热损伤区域的有限元分析[J].中国医学物理学杂志,2007,24(3):197-199. 被引量:4
  • 2Tungjitkusolmun S ,Woo EJ ,Cao H ,et al. Finite element analyses of uniform current density electrodes for radio-frequency cardiac ablation [ J ]. IEEE Trans Biomed Eng,2001,47 ( 1 ) : 32 -40.
  • 3Goldberg SN. Radiofrequency tumor ablation: principles and techniques[ J]. Eur J Ultrasound,2001,13(2) :129 -147.
  • 4Cosman E. Radiofrequency lesions [ M ]//. Gildenberg PL, Tasker R, eds. Textbook of stereotactic and functional neurosurgery. Kingsport : Quebecor Printing, 1996:973 -985.
  • 5Isaac Chang. Finite Element Analysis of Hepatic Radiofrequency Ablation Probes using Temperature-Dependent ElectricalConductivity[ EB/J]. BioMed Central. BioMedical Engineering OnLine, 2003.
  • 6Johansson JD, Eriksson O, Wren J, et al Radio-frequency lesioning in brain tissue with coagulation-dependent thermal conductivity: modelling, simulation and analysis of parameter influence and interaction [ J ]. Med Bio Eng Comput,2006,44 : 757 -766.
  • 7Pennes HH. Analysis of tissue and arterial blood temperatures in theresting human forearm [ J ]. J Appl Physiol, 1948,1:93 - 122.
  • 8Gabriel C, Gabriel S, Corthout E. The dielectric properties of biological tissues : I. Literature survey [ J ]. Physics in Medicine and Bbiology, 1996,41 ( 11 ) :2231 -2250.
  • 9Duck AF. Physical properties of tissue [ J ]. Cambridge: The University Press, 1990.
  • 10Chato JC. Selected thermophysical properties of biological materials [ M ]. Shitzer A, Eberhart R, eds. Heat transfer in medicine and biology : analysis and applications, 1985:413 -418.

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同被引文献93

  • 1纪秀娟,赵宏辉,刘巍.宫腔镜检查异常性子宫出血97例分析[J].哈尔滨医药,2005,25(4):32-33. 被引量:3
  • 2赵镇南,李丰彤.肿瘤射频热疗比吸收率与温度场仿真及影响参数的研究[J].生物医学工程学杂志,2005,22(5):901-905. 被引量:2
  • 3中华人民共和国卫生部.中药新药临床指导原则[M].北京:人民卫生出版社,1993.210.
  • 4丰有吉,沈铿.妇产科学[M].北京:人民卫生出版社,2012.331-334.
  • 5Wilson EA,Yang F,Reese E. Estradiol and progesterone binding in uterine leiomyomata and in normal uterine tis- sues [J]. Obstet Gynecol, 2013,55 ( 1 ) : 20-24.
  • 6Andersen J. Factors in fibroid growth [J]. Baillieres Clin Obstet Gynaecol, 2010,12 (2) : 225 -243.
  • 7Reim MS, Barbier RL, Friedman AJ. Progesterone : a critical role in the pathogenesis of uterine myoma [J]. Am J Obstet Gynecol,2012,172(1 Pt 1 ) : 14-18.
  • 8Murphy AA,Kettel LM,Morales AJ,et al. Regression of uterine leiomyomate in response to the antiprogesterone RU486 [J]. J Clin Endocrinol Metab ,2013,76( 1 ):513.
  • 9Reinsch RC, Murphy AA, Moral AJ,et al. The effects of RU486 and leuprolide acete on uterine artery blood flow in the fibroid uterus:a prospective randomized study [J]. Am J Obstet Gynecol,2012,170(9):1623.
  • 10Brandon DD,Erickson TE,Keenan EJ,et al.Estrogen receptor gene expression in human uterine myomas[J].Am J Obstet Gynecol,1995,14(3):770-772.

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