摘要
目的:探讨早期2型糖尿病肾病的危险因素与防治策略。方法:随机选取120例2型糖尿病患者为研究对象,其中60例为早期糖尿病肾病患者(实验组),60例为尿蛋白正常的患者(对照组),观察2组患者的临床及生化指标。结果:病程、空腹血糖(FBG)、糖化血红蛋白(HbA1c)、血压、总胆固醇(TC)、甘油三酯(TG)、胰岛素抵抗、FIB、Hcy及SUA为影响早期2型糖尿病肾病的危险因素。结论:DN的危险因素主要与胰岛素抵抗、血胆固醇(TC)、FIB及24 h UUA排量增加有关。降血糖、降血压、降尿酸、低蛋白饮食、运动、药物等可以减少早期DN的发生。
Objective：To approach the risk factors and prevention and treatment of incipient diabetic nephropathy in type 2 diabetic pa-tients.Methods：120 patients of T2DM were divided into two groups：60 patients with T2DM without diabetic nephropathy and 60 patients with T2DM complicating diabetic nephropathy .The clinical and biochemical indexes were analyzed both two groups .Results：Diabetic course、FBG、HbA1c、BP、TC、TG、IR、FIB、Hcy、SUA were risk factors of incipient Diabetic Nephropathy in Type 2 Diabetic PatientsC.on-clusion：Risk factor of diabetic nephropathy is possibly associated with IR 、high TC、high FIB and increased 24 h UUA.Strict blood glu -cose control、antihypertensive treatment、limitation of uric acid、limitation of dietary protein intake、movement、medicine could reduce dia-betic nephropathy .
出处
《中国伤残医学》
2014年第8期15-17,共3页
Chinese Journal of Trauma and Disability Medicine
关键词
糖尿病肾病
危险因素
防治策略
Diabetic nephropathy
Risk factors
Prevention and treatment
