摘要
本文观察了磷酸喹哌和汉防己甲素治疗大鼠实验性矽肺的疗效。观察4至10个月。主要观察指标为:病理组织检查、X线检查、肺脏器系数、肺胶原及血清铜蓝蛋白。结果提示:这两种药物对大鼠矽肺有一定疗效。主要表现为:治疗组的矽肺病理改变及X线表现都普遍较同期染尘对照组轻,治疗组的肺脏器系数、肺胶原及血清铜蓝蛋白含量普遍低于对照。
The therapeutic effects of piperaquini phosphas and tetrandrine on experlmental silicosis in rats were observed. The experimental silicosis were induced by intratracheal instillation of silica dust. The period of obser/ation was 4-10 months. Results showed that the two kinds of drug have some therapeutic effects on experimental silicosis of rats. The pathological changes, X-ray manifestations, dry and wet weights of lungs, amount of collagen in the lungs, and amount of copper-protein in seum in the treated groups were generally less than those in positive controls.
出处
《贵阳医学院学报》
CAS
1991年第1期61-65,共5页
Journal of Guiyang Medical College
关键词
磷酸喹哌
汉防己甲素
矽肺
piperaquini phosphas
trine
silicsis
Rat
