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伏核内微量注射5-HTP对大鼠血压的影响 被引量：1

The Effect of MicroinjectionS-HTP into Nucleus Accumbens Rat's Blood Pressnre
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摘要 在大鼠伏陔微量注射5-羟色胺酸(5-HTP)(10μg/2μl)后发现,大鼠血压逐渐下降,以注射后15min至40min时下降最为显著,其机制尚待探讨。 Many Scientists have found that 5-HT plays a role in regulating cardiovascular system, but whether if induce a pressor or a depressor reaction is always paratoxical in our work, when we microinjected 5-HTP (10μg/2μl) into nucleus accumbens of rats, the blood pressure decreaed gradually, began at 15 min after microinjection, significantly at 4.0 min.The mechanism nees to explore.
作者 潘娅 陈灿 刘迪成 蒋乃昌 陆遵华
机构地区 贵阳医学院生理学教研室
出处 《贵阳医学院学报》 CAS 1991年第1期16-18,共3页 Journal of Guiyang Medical College
关键词 5-羟色胺酸 伏核 血压 5-HT 5-HTP rat blood pressured nucleu accumbens
分类号 R338.26 [医药卫生—人体生理学]
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参考文献1

  • 1[荷兰]尼尤温荷斯(R·Nieuwenhuys)等 著,芦鹏等.人类中枢神经系统图谱及注释[M]人民卫生出版社,1984.

同被引文献21

  • 1许慧,李多伟,任静,孙诗清.正交试验法优选5-羟基色氨酸的提取工艺[J].西北药学杂志,2006,21(2):61-63. 被引量：4
  • 2王建军.利用工程菌株BL21-DE3发酵获取5-羟基色氨酸的方法[P].CN:201010183157.8,2008:12.
  • 3Kema I P, DeVries E G E, Muskiet F A J, Clinical Chemistry of Serotonin Metabolites [J].J. Chrom.B.,2000,747(1):33-48.
  • 4Harumi T, Matsushima Sh, Separation and Assay Methods for Melatonin and Its Precursors[J]. Journal of Chromatograplry B, 2000,747(1):95-110.
  • 5Michael M et al. Stimulatory Effects of 1-5-Hydroxytryphophan on Postdexamethasome β-Endorphin Levels in Major Depression[J]. Neuropsychopharmacology,1996,15(4):340-348.
  • 6Ohgi Y., Futamura T., Kikuchi T., et al. Effects of Antidepressants on Alternations in Serum Cytokines and Depressive-like Bchavior in Mice after Lipopolysaccharide Administration [J]. Pharmacol Biochem Behav.,2013,103(1):853-859.
  • 7Gendle M. H., Young E. L., Romano A. C. Effects of Oral 5-Hydroxytryptophan on a Standardized Planning Task: Insight into Possible Dopamine/Serotonin Interactions in the Forebrain[J]. Hum Psychopharmacol,2013,28(3):270-273.
  • 8Jangid P., Malik P., Singh P, et al. Comparative Study of Efficacy of 1-5-Hydroxytryptophan and Fluoxetine in Patients Presenting with First Depressive Episode[J]. Asian J Psychiatr.,2013,6(1):29-34.
  • 9Abdala-Valencia H., Berdnikovs S. McCary C.A.,et al. Inhibition of Allergie Inflammation by Supplementation with 5-hydroxytryptophan[J]. Am. J. Physiol Lung Cell Mol, Physiol.,2012,303(8):642-660.
  • 10Laporta J., Peters T. L., Weaver S. R. et al. Feeding 5-Hydroxy-1-Tryptophan During the Transition from Pregnancy to Lactation Inereases Calcium Mobilization From Bone in Rats[J]. Domest Anim Endocrinol,2013,44(4):176-184.

引证文献1

贵阳医学院学报
1991年 第1期

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