摘要
目的探讨氟桂利嗪联合尼莫地平治疗偏头痛的临床疗效。方法将2012-03—2013-03本院收诊的偏头痛患者随机分成对照组和观察组各88例。对照组采用氟桂利嗪治疗,观察组采用氟桂利嗪联合尼莫地平治疗。治疗前后对2组患者的症状进行量化评分,比较组间差异;比较2组疗效差异。结果治疗12周后,观察组痊愈率显著高于对照组,无效率显著低于对照组,P<0.05;治疗组总有效率94.32%,显著高于对照组的80.68%,P<0.05。治疗4、12周后观察组疼痛程度、头痛发作次数、持续时间、伴随症状及总症状量化评分均显著低于对照组,(P<0.05)。结论氟桂利嗪联合尼莫地平治疗偏头痛能有效改善偏头痛症状,疗效优于单用氟桂利嗪。
Objective To investigate the clinical efficacy of flunarizine combined with nimodipine for the patient with mi- graine. Methods Patient with migraine from March 2012 to March 2013 were randomly divided into control group（flunarizine treatment group）88 cases and observation group（flunarizine combined with nimodipine group）88 cases,then the quantify symp- tom score of two groups before the treatment and after the treatment were compared. The difference in efficacy between the two groups after completion of treatment were also been counted. Results After 12 weeks of treatment, the cure rate of observation group was significantly higher than the control group, no efficiency is significantly lower than the control group, and the total effective rate was 94.32% which was significantly higher than the 80.68% of control group, all P〈0.05. After 4 and 12 weeks of treatment, the quantify symptom scores of pain, headache frequency, duration, associated symptoms and total symp- tom were all lower than those indexes of control group,all P〈0.05. Conclusion The influence of flunarizine combined with ni- modipine for the patient with migraine is great,and it is more effective for the improvement of migraine symptoms.
出处
《中国实用神经疾病杂志》
2014年第5期37-38,共2页
Chinese Journal of Practical Nervous Diseases
