摘要
目的 :观察维生素C联合地塞米松治疗眼部碱烧伤的疗效 ,并探讨其作用机制。方法 :将 6 4例眼部碱烧伤患者按碱性物质及烧伤程度相同 ,年龄、就诊时间相近配成对子 ,共 32对 ,并将每对中的两名患者随机分配到治疗组和对照组 ,其中治疗组用维生素C和地塞米松联合治疗 ,对照组单独用维生素C治疗 ,同时两组均口服维生素A和维生素B2 ,结膜囊内滴抗菌素眼液 ,以视力的恢复情况为标准比较两组的疗效。结果 :视力恢复达 0 .5以上者 ,治疗组占 78.1% ,对照组 46 .9%。经t检验两组有显著性差异。结论 :在眼部碱烧伤中用维生素C联合地塞米松治疗效果好 ,只要适当掌握地塞米松的应用时机 ,使用地塞米松是安全的 ,有效的。
Objective:To observe the effect treating ocular alkali burn with vitaminC and dexamethasone,discuss their mechanism.Methods:64 patients were divided into 32 couples by same alkali materials,burn degrees and similar ages,burnt time between a couple.Two patients of a couple were randomly assigned to treatment group and control group,treatment group received vitaminC,dexamethasone and control group received vitaminC alone.The effect of two groups was compared by recovery of visual acuity.Results: It was 78.1% in treatment group and 46.9% in control group that corrected visual acuity was 0.5 or over.The difference was statistically significant.Conclusions:It is safe and effective to use dexamethasone so long as the proper time of using it is uderstood in ocular alkali burn.
出处
《中国现代医学杂志》
CAS
CSCD
2001年第2期16-17,共2页
China Journal of Modern Medicine
关键词
碱烧伤
维生素C
地塞米松
视力
Alkali Burn
VitaminC
Dexamethasone
Visual Acuity
