摘要
目的 :评价利巴韦林葡萄糖注射液对急性病毒性上呼吸道感染的疗效及安全性并与利巴韦林注射液进行比较。方法 :160例体温在 38.5℃以上的急性病毒性上呼吸道感染病人 ,采用区组随机对照法分为利巴韦林葡萄糖注射液组 (验证组 ) 10 0例和利巴韦林注射液组 (对照组 ) 60例 ,剂量均为 50 0mg ,iv ,gtt,bid× 5d。结果 :验证组和对照组的临床有效率为 97%和 92 % ,组间经 χ2 检验 ,差别无显著意义 (P >0 .0 5) ;2组有显著的退热作用和抗病毒作用 ,不良反应轻微。结论
AIM: To evaluate the therapeutic effects and safety of ribavirin glucose injection and ribavirin (Virazole) injection in the treatment of acute viral upper respiratory tract infection. METHODS: One hundred and sixty hyperthermia (T≥ 38.5℃ ) patients with acute viral respiratory tract infection were divided into 2 groups according to method of block random control. A ( n =100) group was given ribavirin and glucose injection (tratment group), 500 mg,iv, g tt , bid for 5 d, another (n =60) was given ribavirin injection (control group) 500 mg, iv, g tt , bid for 5 d. RESULTS: The clinical effective rate was 97% in treatment group and 92% in control group, there was no significant difference between 2 groups by χ 2 test ( P >0.05); it was showed that 2 groups had significant reducing fever action and antivirotic action, adverse reactions were mild. CONCLUSION: Ribavirin and ribavirin glucose injection as well as ribavirin injection is an effective and safe drug in the treatment of acute viral upper respiratory tract infection.
出处
《中国新药与临床杂志》
CAS
CSCD
北大核心
2001年第1期25-27,共3页
Chinese Journal of New Drugs and Clinical Remedies
关键词
利巴韦林
剂型
病毒性疾病
药物评价
ribavirin
dosage forms
virus diseases
drug evaluation
