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利奈唑胺治疗重症监护病房脓毒症患者的疗效与安全性评价 被引量:4

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摘要 目的对利奈唑胺在重症监护病房(ICU)脓毒症治疗方面的疗效和安全性进行评价。方法对我院经利奈唑胺治疗脓毒症患者52例的资料进行分析,评价其疗效,同时记录治疗期间的不良反应。结果本组52例患者中总有效率为75.0%。治疗后患者APACHEⅡ评分、血乳酸及炎性因子TNF-a、IL-6均较治疗前明显降低,与治疗前比较差异具有显著性(P<0.05)。6例发生不良反应,不良反应发生率为11.5%,未经特殊处理,停药后恢复。结论利奈唑胺治疗脓毒症效果显著,安全性较高,有指征的应用对提高救治率,挽救患者生命具有积极的作用。
出处 《中国药物经济学》 2014年第3期12-12,18,共2页 China Journal of Pharmaceutical Economics
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