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妥洛特罗透皮贴剂在慢性气道疾病治疗中的应用 被引量:7

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摘要 慢性气道疾病是呼吸系统的常见病,其发病率高,病程长,严重影响患者的生活质量.支气管哮喘(简称哮喘)和慢性阻塞性肺疾病(COPD)是两大主要的慢性气道疾病.哮喘是由多种细胞和细胞组分参与的气道慢性炎症性疾病,可导致气道反应性升高,通常出现广泛多变的可逆性气流受限,并引起反复发作的喘息、气急、胸闷或咳嗽等症状.如诊治不及时,随病程延长可产生气道不可逆性狭窄和气道重塑,控制不良会严重限制患者的日常活动,急性发作亦可危及生命.COPD是以气流受限为特征的肺部疾病,气流受限不完全可逆,呈进行性发展.因肺功能进行性减退,严重影响患者的劳动能力和生活质量.WHO的资料显示,COPD的死亡率居所有死因的第4位,且有逐年增加之势.支气管舒张剂在哮喘和COPD的治疗中均占重要地位,近年来,不断有新的支气管舒张剂剂型应用于临床.现就新型支气管舒张剂——妥洛特罗透皮贴剂在哮喘和COPD治疗中的应用综述如下.
出处 《中华内科杂志》 CAS CSCD 北大核心 2014年第4期334-336,共3页 Chinese Journal of Internal Medicine
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参考文献23

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