摘要
目的：探讨辛伐他汀对冠心病合并心力衰竭的疗效。方法回顾性分析2010年2月～2012年10月广东省增城市派潭镇中心卫生院收治的80例冠心病合并心力衰竭患者的临床资料，随机平均分为2组（n=40），对照组采用基础治疗措施和观察组采取基础治疗联合辛伐他汀，观察分析治疗前后血清TC、LDL-C和CRP的测定水平，并且进行左室射血分数的测量和6min步行试验。结果治疗前2组在TC、LDL-C和CRP指标方面无显著差异，治疗后观察组患者的TC值为（4.03±2.06）mmol/L，LDL-C值为（2.35±0.21）mmol/L，CRP值为（8.3±5.65）mg/L，显著低于对照组，差异显著。结论在基础治疗的基础上联合辛伐他汀治疗冠心病合并心力衰竭，能够改善心功能降低血脂，值得临床应用。
Objective To investigate the effect of simvastatin on coronary heart disease complicated with heart failure.Method 80 cases with Coronary heart disease （CHD） combined heart failure in our hospital from February 2010 to October 2012 were divided randomly into two groups. 40 patients in the control group were received basic treatment measures and 40 patients in the observation group were given simvastatin on the base of basic treatment. Before and after treatment, TC, LDL-C, CRP, left ventricular ejection fraction and 6min walk test were tested.Results Before treatment the two groups on TC, LDL-C and CRP indexes had no significant difference, after treatment, patients in the observation group TC value was （4.03±2.06） mmol/L, LDL-C value was （2.35±0.21） mmol/L, CRP value was （8.3±5.65） mg/L, significantly lower than the control group, the difference was significant.Conclusion The basic treatment of coronary heart disease with heart failure combined treatment with simvastatin can improve heart function and blood lipids, therapeutic effect is better way.
出处
《当代医学》
2014年第10期113-114,共2页
Contemporary Medicine
关键词
冠心病
心力衰竭
辛伐他汀
Coronary heart disease
Heart failure
Simvastatin
