摘要
选取2010年6月至2011年2月郑州市6个社区40岁以上女性常住居民6 785名,根据血糖水平分为血糖正常组（NC组）、血糖调节受损（IGR）组与糖尿病组（DM组）,比较3组人群在子女数量、年龄、血脂、血压、腰围、臀围、体质指数（BMI）以及饮酒、吸烟、哺乳等方面的差异.以logistic回归分析糖尿病发生风险.结果显示,NC组3 170例、IGR组2 035例,DM组1 580例.NC组子女数量为4（0,8）个,IGR组子女数量为5（0,10）个,DM组子女数量为5（0,10）个,差异有统计学意义（F=100.95,P ＜0.05）.经logistic回归显示,子女数量与IGR、糖尿病的发生风险存在正相关性,随着子女数量的增加,血糖代谢恶化的风险升高（OR：1.115,95％ CI：0.063～0.156,P＜0.05）.结果表明生育子女数量的多少与中老年女性发生IGR和糖尿病的风险存在相关性,并且生育子女数增多可能是中老年女性发生IGR和DM的危险因素之一.
A total of 6 785 female participants were collected,containing 3 170 orthoglycemic women（NC group）,2 035 impaired glucose regulation women（IGR group） and 1 580 diabetic women （DM group）.The clinical data were investigated,including the number of children,age,serum lipids,blood pressure,waist and hip circumference,smoking,drinking,and so on.The association between increasing number of children and glucose metabolic status was evaluated by stepwise logistic regression.Among the NC group （n =3 170）,IGR group （n =2 035） and DM group （n =1 580）,there was significant difference in the number of children that NC group has least children with a mean of 4 （0,8）,and DM group has most children with a mean of 5 （0,10）.In a full model,after controlling other factors,the number of children had a significant positive influence on the diabetes risk of middle-aged women （OR： 1.115,95% CI： 0.063-0.156,P 〈0.05）.The number of children was associated with IGR and DM in middle-aged women,and this relationship seemed to suggest grand multiparity may be one risk factor of IGR and DM in middle-aged women.
出处
《中华糖尿病杂志》
CAS
CSCD
2014年第3期184-186,共3页
CHINESE JOURNAL OF DIABETES MELLITUS
关键词
糖尿病
子女数量
糖调节受损
Diabetes
Number of children
Impaired glucose regulation
