摘要
[目的 ]探讨桃仁提取物 (苦杏仁甙 )抗矽肺纤维化作用。 [方法 ]采用桃仁提取物治疗矽肺大鼠 ,观察矽肺胶原蛋白和生化指标变化 ,及对大鼠矽肺病理影响。 [结果 ]桃仁提取物能显著抑制矽肺大鼠胶原蛋白合成和减少血清铜蓝蛋白。 [结论
Objective] This study is to study the anti fibrotic effects of semen persicae extract(amygdalin)in rats.[Methods] Silicotic rats were treated with semen persicae extract to study the changes of silicotic collagen,biochemical indices and effects on pathology of silicotic rats.[Results] Semen persicae extract significantly restrained synthesis of collagen and reduced ceruloplasmin in serum of silicotic rats.[Conclusion] Semen persicae extract inhibited remarkably silicotic fibrosis in rats.
关键词
桃仁提取物
矽肺纤维化
胶原蛋白
semen persicae extract
silicotic fibrosis
collagen
