摘要
目的观察天灸对慢性阻塞性肺疾病(COPD)稳定期患者生命质量、炎症介质(IL-8、TNF-α)及T细胞亚群(CD4、CD8、CD4/CD8)的影响。方法将慢性阻塞性肺疾病稳定期患者320例,随机分为治疗组和对照组,治疗组160例,对照组160例,以药物(处方:白芥子、细辛、甘遂、麻黄、干姜、吴茱萸)敷贴穴位。对照组160例,采用安慰剂敷贴穴位。结果通过约3年的天灸治疗后,治疗组能够较对照组能降低COPD稳定期患者生命质量(呼吸症状、活动受限、疾病影响、总分积分)评分分值、降低炎症介质(IL-8、TNF-α)表达、提高T淋巴细胞亚群指标(CD4、CD8、CD4/CD8)表达水平。结论天灸疗法能够在一定程度上降低炎症反应,提高肌体免疫力,达到改善生命质量目的。
Objective To observe the impacts of festering moxibustion therapy on the life quality, inflammatory mediators（IL-8,TNF -α）and T cell subsets（CD4,CD8 and CD4/CD8）in the patients of chronic obstructive pulmonary disease（COPD）at stable stage.Methods Three hundred and twenty cases of COPD at stable stage were randomized into a treatment group and a control group,1 60 cases in each one.The herbal festering moxibustion （semen brassicae,asarum,euphorbia kansui,ephedra,rhizoma zingiberis and fructus evodiae）was applied at the acupoints in the treatment group.The placebo moxibustion was used at the acupoints.Results After the festering moxibustion treatment for about 3 years,the score of life quality（respir-atory symptoms,limited activity,disease impact and total score）was reduced,the expressions of inflammatory mediators（IL-8,TNF-α）were reduced and the expressions of T cell subsets（CD4,CD8 and CD4/CD8）were improved in the treatment group as compared with the control group.Conclusion The festering moxibustion therapy reduces inflammatory reaction and improves body immunity and life quality to certain extent.
出处
《世界中西医结合杂志》
2014年第3期263-265,共3页
World Journal of Integrated Traditional and Western Medicine
基金
江西省卫生厅中医药管理局指导性课题(No.2011A104)
关键词
天灸疗法
COPD稳定期
生命质量
炎症介质
T细胞亚群
Festering Moxibustion Therapy
COPD at Stable Stage
Life Quality
Inflammatory Medi-ators
T Cell Subsets
