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心肌梗死后心室重塑的治疗新靶点:免疫细胞中介的炎症反应 被引量：3

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摘要 心肌梗死是引起全球范围内致死和致残的主要病因之一。心肌梗死后缺血区心肌的功能丧失可通过Laplace定律以心室腔的扩大为代价，维持射血分数；但长时间室壁应力的增加势必引起心室梗死区和非梗死区结构和功能的改变，进而导致心力衰竭出现。目前的临床治疗主要通过早期再灌注治疗减少梗死面积，同时降低左心室负荷，从而改善心肌梗死后的心室重塑。
作者 卢芮伊 周欣 姬文婕 李玉明
机构地区 武警后勤学院附属平津医院中国武警心脏医院心内科武警部队心血管病研究所天津市心血管重塑与靶器官损伤重点实验室
出处 《中华临床医师杂志（电子版）》 CAS 2013年第24期11-13,共3页 Chinese Journal of Clinicians(Electronic Edition)
基金 国家自然科学基金(81070121 81102088 81170238)
关键词 心肌梗死 再灌注治疗 心室重塑 炎症反应 免疫细胞 死后 新靶点 Laplace定律
分类号 R542.22 [医药卫生—心血管疾病]
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参考文献31

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共引文献22

同被引文献42

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二级引证文献9

中华临床医师杂志（电子版）
2013年 第24期

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