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过敏原减敏治疗联用小剂量酮替酚对气道高反应性的作用

EFFECT OF ALLERGIC IMMUNOTHERAPY AND SMALL DOSE KETOTIFEN ON AIRWAY HYPERREACTIVITY
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摘要 过敏原浸出液减敏疗法已广泛应用于外源性支气管哮喘的治疗,疗效基本肯定;其缺点是起效慢、疗程长,高度敏感的病人易出现副作用。 The purpose of this study is to observe the effects of following therapies on bronchial reactivity: immunotherpy and ketotifen (ordinary and small dose) alone or in combination, or bronchodilator drugs alone. 94 cases of allergic asthna were randomly divided into 4 groups and were treated with different therapy for 6 months. The result shows that the combination of immunotherapy and ketotifen can raise PD 20-PEF and reduce the positivity rates of NPT more markedly and quickly than allergic im- munotherapy alone. Bronchodilator drugs can increase PEF but can not improve PD20-PEF, And there are no significant difference between ordinary and small dose ketotifen groups. We conclude that allergic immunotherapy and small dose ketotifen can decrease bronchial hyperreactivity markedly and quickly, without obvious side effects.
出处 《广东医学》 CAS CSCD 1991年第1期37-39,共3页 Guangdong Medical Journal
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