摘要
目的:探讨华蟾素胶囊对癌性疼痛的临床疗效。方法:将我院治疗的63例恶性肿瘤患者随机分为治疗组33例和西药组30例,西药组采用口服硫酸吗啡,治疗组口服华蟾素胶囊,对比两组治疗癌性疼痛的效果、不良反应发生率、起效时间、生活质量以及KPS和NRS评分。结果:治疗组的总有效率为93.9%,西药组为86.7%,两组无统计学差异(P>0.05);治疗组平均起效时间为(11.4±4.7)min,西药组为(29.6±5.61)min,两组相比,具有统计学差异(P<0.05);治疗后两组体重相比,治疗组体重增加率为87.9%,高于西药组60.0%(P<0.05)。两组KPS评分和NRS评分相比,无统计学差异(P>0.05)。结论:华蟾素对癌性疼痛效果明显,起效快,不良反应低。
Objective：To explore the clinical efficacy of cinobufacini Capsule on cancer pain.Methods： Select 63 cases of patients with malignant tumor in our hospital, were randomly divided into treatment group 33 cases and western medicine group of 30 cases,western medicine group were treated with oral administration of morphine sulfate, treatment group was treated with cinobufacini capsule.Comparing the two groups in the treatment of cancer pain effect, adverse reaction incidence, onset time, quality of life as well as the KPS and NRS score.Results：The total effective rate in treatment group was 93.9%, control group 86.7%, two groups had no significant difference （P〉0.05）.The average onset time of treatment group was （11.4±4.7） min, the western medicine group （29.6±5.61） min, compared to the two groups, with statistical difference （P〈0.05）.The two groups after treatment compared weight gain weight, the treatment group was 87.9%, higher than the western medicine group of 60%（P〈0.05）.Compared two groups of KPS and NRS scores, there are no significant difference （P〉0.05）.Conclusion：Effect of cinobufacini on cancer pain effect, fast acting, less adverse reactions.
出处
《中国医药导刊》
2014年第3期478-479,481,共3页
Chinese Journal of Medicinal Guide
关键词
华蟾素
癌性疼痛
疗效观察
Cinobufacini
Cancer pain
Clinical effect
