摘要
目的：探索胺碘酮不同给药方法治疗恶性心律失常的临床疗效。方法：选取我院在2009年6月至2012年6月期间收治的恶性心律失常患者60例,随机分为两组：治疗组和对照组各30例。对照组患者予以单纯胺碘酮药物3-5mg/kg静脉注射治疗,治疗组患者在对照组静脉注射治疗基础上联合胺碘酮口服给药进行治疗。结果：在治疗总有效率方面,两组患者比较,P〉0.05,差异不具有统计学意义；在24h后复发率以及并发症发生率方面,治疗组均显著低于对照组（P〈0.05）；在患者及其家属满意率方面,治疗组显著高于对照组,均P〈0.05,差异有统计学意义。结论：运用胺碘酮静脉注射联合口服药物治疗恶性心律失常临床治疗效果好,有利于减少并发症并降低复发率,并且安全性以及患者满意度较高。
Objective：To explore the clinical efficacy of different administration methods of amiodarone in treatment of malignant arrhythmia. Methods：60 patients with malignant arrhythmia in our hospital during 2009 June to 2012 in June, were randomly divided into two groups：the treatment group and the control group with 30 cases in each. Patients in the control group received only Amiodarone Drug 3-5mg/kg intravenous therapy, patients in the treatment group in the control group treated by intravenous injection of amiodarone combined oral administration treatment. Results：the total efficiency in treatment, compared two groups of patients, P〉0.05, the difference is not statistically significant;in the recurrence rate and complication rate after 24h, the treatment group were significantly lower than those in the control group （ P〈0.05 ）;the ratio of the patients and their families, the treatment group was significantly higher than that in control group, P〈0.05, statistical significance of difference. Conclusion：the use of amiodarone intravenous injection and oral administration of drugs in the treatment of malignant arrhythmia clinical treatment effect, reduce complications and lower recurrence rate, and safety and with a higher patient satisfaction.
出处
《中国医药导刊》
2014年第3期467-468,共2页
Chinese Journal of Medicinal Guide
关键词
恶性心律失常
胺碘酮
口服
静脉给药
疗效对比
Malignant arrhythmia
Amiodarone
Oral
Intravenous injection
Curative effect contrast
