摘要
目的：探讨苯磺酸左旋氨氯地平联合依那普利治疗原发性高血压的疗效和安全性。方法：将2011年6月-2013年2月期间本院收诊的原发性高血压患者随机分成两组,对照组和观察组各92例,对照组采用依那普利治疗,观察组采用苯磺酸左旋氨氯地平联合依那普利治疗。治疗前后对两组血压进行测量,比较疗效差异；同时对患者的肝肾功能进行检测,并统计不良反应发生率。结果：治疗4、12周后,观察组患者24hSBP和24hDBP均显著低于对照组,P〈0.05。观察组患者显效率和总有效率均显著高于对照组,P〈0.05。观察组不良反应发生率低于对照组,P〉0.05。结论：苯磺酸左旋氨氯地平联合依那普利治疗原发性高血压疗效好,且安全性高。
Objective：To evaluate the safety and efficacy of Levamlodipine and enalapril in the treatment of essential hypertension. Methods：Patients in our hospital diagnosed with essential hypertension during the period from June 2011 to February 2013 were randomly divided into two groups,the control group and the observation group,and 92 cases in each group. The control group was taken with enalapril treatment,and the observation group was treated with Levamlodipine besylate combined enalapril treatment.The blood pressure before and after treatment in the two groups was taken for measurement.The differences of the efficacy were compared.The function of liver and kidney at the same time was taken for detection.The incidence rate of adverse reaction was taken for statistics.Results：4,12 weeks after treatment,24h SBP and 24h DBP for patients in the observation group were significantly lower than those in the control group,P〈0.05.The markedly effective rate and total effective rate in the observation group were significantly higher than those in the control group,P〈0.05. The adverse reaction in the observation group was lower than that of the control group,P〉0.05.Conclusion：The efficacy of levamlodipine and enalapril in the treatment of primary hypertension is good, and with higher safety.
出处
《中国医药导刊》
2014年第2期266-267,共2页
Chinese Journal of Medicinal Guide
