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厄贝沙坦与不同降压药物联合治疗原发性高血压的疗效与药物临床观察 被引量:19

Observation on the Curative Effect of Drug Therapy Combined with Irbesartan and Different Antihypertensive Drugs in Essential Hypertension
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摘要 目的:观察在原发性高血压药物治疗过程中使用厄贝沙坦联合非洛地平或雷米普利的疗效及安全性,以探寻更好的治疗高血压方案。方法:选择2010年1月-2012年10月我院收治的原发性高血压患者90例为研究对象,随机分为两组,实验组给予厄贝沙坦联合非洛地平治疗,对照组给予厄贝沙坦联合雷米普利治疗,观察两组治疗效果与不良反应。结果:实验组患者45例,有效42例,总有效率高于对照组患者,P〈0.05,差异有统计学意义;实验组与对照组患者的不良反应比较P〉0.05,差异无统计学意义。结论:使用厄贝沙坦联合非洛地平对原发性高血压患者可以取得较好的疗效,其总有效率高于厄贝沙坦联合雷米普利的总有效率,且安全性较高,患者不良反应少,值得应用。 Objective:To observe the efficacy and safety of irbesartan and felodipine or use of ramipril in essential hypertension in the process of drug treatment of hypertension treatment, to explore a better scheme.Methods:from January 2010 to October 2012 in our hospital with essential hypertension 90 patients for the study were randomly divided into two groups, given irbesartan in combination with felodipine treatment, the control group was given irbesartan ramipril treatment were observed effect.Results:The experimental group 45 cases, effective in 42 cases, the total efficiency than those of controls, p〈0.05, the difference was statistically significant;adverse reactions in patients in the experimental group and control group comparison P〉0.05, the difference was not statistically significant.Conclusion:The use of irbesartan in combination with felodipine in patients with essential hypertension can achieve better efficacy, and security is good, it is worth Application.
出处 《中国医药导刊》 2014年第1期131-132,共2页 Chinese Journal of Medicinal Guide
关键词 厄贝沙坦 联合 原发性高血压 治疗效果 Irbesartan joint Essential hypertension Therapeutic effect
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