摘要
目的:探讨舒利迭联合噻托溴胺吸入治疗慢性阻塞性肺疾病的临床疗效。方法:将110例患者随机分为对照组53例和观察组57例。除常规治疗外,对照组给予舒利迭2次/d,观察组额外给予噻托溴胺1次/d,治疗12周。于治疗前后分别测定肺功能FEV1(L)、FEV1(%)、FEV1/FVC(%)。结果:经治疗后两组患者肺功能均有显著改善(P<0.05)。观察组肺功能指标明显高于对照组(P<0.05),结论:舒利迭与噻托溴胺联合使用治疗慢性阻塞性肺疾病疗效良好,可显著改善肺功能,不良反应较小,效果优于单用舒利迭。
Objective：To observe the effect of Seretide and tiotropium in the treatment of chronic obstructive pulmonary disease （COPD）.Methods：120 patients were randomly divided into observation group with 57 cases and control group with 53 cases, both groups were given conventional therapy.The control group was given Seretide twice a day, the observation group was given Seretide twice a day and tiotropium once a day.Two groups were treated for 12 weeks. Pulmonary function FEV1（L）,FEV1（%）and FEV1/FVC（%） of two groups were detected before and after treatment.Results：Two groups with chronic obstructive pulmonary disease significantly improve after treatment（P〈0.05）;Compared with the control group after treatment, lung function index of the observation group increased significantly（P〈0.05）.Conclusion：Serefide and tiotropium can improve lung function of the parents with COPD obvious,curative effect is better than serefide.
出处
《中国医药导刊》
2014年第1期123-124,共2页
Chinese Journal of Medicinal Guide
