摘要
目的：了解隆阳区不同年龄段麻疹免疫球蛋白G （IgG）抗体水平，为计划免疫工作提供科学依据。方法采取分层整群抽样方法，应用酶联免疫吸附试验（ELISA）测定398例健康人群血清麻疹IgG抗体水平。结果共抽样本398例，麻疹抗体阳性358例，麻疹抗体阳性率89．95％；各年龄组间麻疹抗体水平比较差异有统计学意义（F＝2．494，P＝0．016）；各乡镇间麻疹IgG抗体水平比较差异有统计学意义（F＝12．467，P＝0．000）；麻疹疫苗接种剂次与麻疹IgG抗体水平比较差异无统计学意义（F＝0．771，P＝0．545）。结论隆阳区麻疹IgG抗体处在较高水平，已建立有效免疫屏障，对边远山区麻疹IgG抗体水平相对较低和13～＜18岁青少年适时强化免疫，防止发生小规模爆发。
Objective To learn about the measles immunoglobulin G （IgG） antibody levels of different age groups in Longyang district so as to provide the scientific basis for the planned immunization program. Methods By adopting the stratified cluster sam-piing method,serum antibody level of measles IgG was detected in 398 healthy people by the enzyme-linked immunosorbent assay （ELISA）. Results 398 samples were collected and 358 cases were positive measles antibody with the measles antibody positive rate of 89.95% ;the measles antibody levels had statistical difference among the different age groups （F=2. 494, P=0. 016）;the mea-sles antibody levels had statistical difference among the different townships （F=12. 467, P=0. 000） ;there was no statistical differ-ence between the times of measles vaccination and the measles IgG antibody level （F=0. 771 ,P=0. 545）. Conclusion The measles IgG antibody in Longyang district is at a high level and the effective immune barrier has been built. The teenagers with relatively low Ig G antibody level in remote mountain areas and aged 13-18 years should be timely given supplementary immunization in or-der to prevent the outbreak of small scale of measles.
出处
《国际检验医学杂志》
CAS
2014年第6期707-708,共2页
International Journal of Laboratory Medicine
关键词
麻疹
酶联免疫吸附测定
measles
immunoglobulin G
enzyme linked immunosorbent assay
