摘要
[目的]观察清胰解毒汤鼻饲加芒硝外敷联合西医治疗重症急性胰腺炎疗效。[方法]使用随机平行对照方法,将25例住院患者按随机数字表法分为两组。对照组12例西医治疗。①一级护理。②奥曲肽0.6mg+0.9%氯化钠48mL,2次/d,静注。奥美拉唑42.6mg+0.9%氯化钠100mL,2次/d,静滴。亚胺培南西司他汀针1000mg+0.9%氯化钠注射液100mL,静滴,3次/d。甲磺酸加贝酯针0.3g+5%葡萄糖注射液500mL,2次/d,静滴。治疗组13例中医特色治疗。①入院后经胃肠减压12h后拔出胃管,经内镜下置入空肠营养管。清胰解毒汤(生大黄后下30g,芒硝溶、枳实、厚朴、黄连、丹参各15g,蒲公英30g,桃仁、柴胡各10g,延胡索15g),加水500mL浓煎至100mL,30mL/次,3次/d,鼻饲。②芒硝外敷。西医治疗同对照组。连续治疗10d为1疗程。观测临床症状、时间指标、不良反应。连续治疗3疗程,判定疗效。[结果]治疗组显效9例,有效3例,无效1例,总有效率88.31%。对照组显效6例,有效4例,无效2例,总有效率72.33%。治疗组疗效优于对照组(P<0.05)。各项时间指标治疗组均少于对照组(P<0.05)。[结论]清胰解毒汤鼻饲加芒硝外敷联合西医治疗重症急性胰腺炎效果显著,值得推广。
[ Objective ] To observe the effect of Qingyi Decoction prescription nasal feeding and mirabilite and Western medicine in the treatment of severe acute pancreatitis. [ Methods ] Using randomized controlled methods, will be divided into two groups according to the random number table, 25 cases of hospitalized patients. The control of Western medicine treatment group of 12 cases. The first level nursing. The Sodium Chloride Injection octreotide 0.6mg ＋ 0.9% 48mL, 2 /d, intravenous injection. Omeprazole Sodium Chloride Injection needle 42.6mg ＋ 0.9% 100mL, 2/d, intravenous drip. Imipenem and statins needle 1000mg＋0.9% Sodium Chloride Injection 100mL, intravenous drip, 3 times/d. Gabexate mesilate needle 0.3g ＋ 5% Glucose Injection 500mL, 2/d, intravenous drip. The characteristics of traditional Chinese medicine in treatment of 13 eases of treatment group. The patient underwent gastrointestinal decompression after 12h pull out tube, the nutrition in jejunal tube under endoscope. Qingyi Jiedu Decoction （ Shengdahuang later 30g, Mangxiao dissolve,Jishi, Houbu, Huanglian, Danshen each 15g, Pugongying 30g, Taoren, Chaihu each 10g, Huyansuo 15g）, add 500ml of water concentrated decoction to 100mL, 30mL/, 3 /d, nasal feeding. The external application of mirabilite. Western medicine treatment with the control group. Continuous treatment with 10d for 1 courses. Observation of clinical symptoms, the time index, adverse reaction. Continuous 3 courses of treatment, the curative effect. 9 cases of group therapy. [ Results ] 3 cases were effective, 1 cases ineffective, the total efficiency of 88.31%. 6 cases of control group, 4 cases effective, 2 cases ineffective, the total efficiency of 72.33%. The treatment group was better than control group （ P〈 0.05 ） . Each time indexes in the treatment group were less than that of the control group （ P〈 0.05 ） . [ Conclusion ] Qingyi Decoction prescription nasal feeding and mirabilite and Western medicine in the treatment of severe acute pancreatitis effect is significant, worthy of promotion.
出处
《实用中医内科杂志》
2014年第1期106-109,共4页
Journal of Practical Traditional Chinese Internal Medicine
关键词
重症急性胰腺炎
清胰解毒汤
芒硝
奥曲肽
奥美拉唑
亚胺培南西司他汀
甲磺酸加贝酯
随机平行对照研究
Severe acute pancreatitis
Qingyi Decoction
Mirabilite
Octreotide
Omeprazole needle
Imipenem and statins needle
Gabexate mesilate needle
Randomized parallel controlled study
