摘要
目的 :探讨广州管圆线虫所致大白鼠心脏的病理变化。方法 :大白鼠感染管圆线虫后 ,用光镜与电镜观察其心脏的形态改变。结果 :感染 30天后的大白鼠右心房室及肺动脉可见成虫寄生 ,心肌纤维变性 ,嗜酸粒细胞浸润 ,内膜细胞脱落 ,外膜有纤维素渗出。电镜下见肌膜高度水肿 ,肌丝溶解 ,线粒体空泡变等。结论 :广州管圆线虫所致大白鼠的心脏病变 ,主要表现为成虫寄生于右心室 ,并可致心内膜。
Purpose To identify the pathological features of heart in rats with Angiostrongylus cantonensis. Methods To observe the morphological changes in the heart of rats infected by Angiostrongylus cantonensis with light and electron microscope. Results Adult worm is parasit in the right heart and pulmonary artery of rats that were infected by Angiostrongylus cantonensis for 30 days,myofibrosis degeneration, eosinophilic cell infiltration, endotheliocyte fall, pericardia fibrin exudation were observed. Ultrastructural findings display high myomembrane edema, lytic myofiber and mitochondrion vacuolar degeneration. Conclusions The rats heart damage results from Angiostrongylus cantonensis. The result shows that adult worm is parasicted in right ventricular and pulmonary artery, which results in endocarditis, myocarditis and pericarditis.
出处
《临床与实验病理学杂志》
CAS
CSCD
2000年第6期504-506,共3页
Chinese Journal of Clinical and Experimental Pathology
基金
浙江省教委资助项目!(No 19990 45 7)
