摘要
利用正交试验,研究了热定型工艺（温度、时间、热定型方式）对聚乙交酯（PGA）单丝及编织线力学性能的影响,并将经过热定型（55℃、拉伸定型5 min）和未经热定型的PGA肌腱支架增强体置于温度为37℃、pH值为7.4的磷酸盐缓冲液中进行4星期的体外降解试验.研究结果表明：热定型温度和时间对PGA单丝及编织线力学性能影响较大.对于PGA单丝及编织线,当热定型温度为40～60℃、时间为3～5 min、采用拉伸定型方式时,其力学性能较好;体外降解试验表明,经过热定型的PGA肌腱支架增强体的力学性能优于未经热定型的肌腱支架增强体.
The influence of heat setting process （temperature, time, heat setting method） on the mechanical property of polyglycolic acid （PGA） fiber and braided yarns were investigated with orthogonal experiment. Both PGA scaffolds before and after heat setting were placed in phosphate buffer solution （pH value is 7.4） at 37℃ for four weeks degradation. The experimental results show that both the heat setting temperature and heat setting time have effect on mechanical property of the PGA fiber and braided yarns. The mechanical property of PGA fiber and braided yarns were better by stretch heat setting method at a temperature within the range of 40 to 60 ℃ and time from 3 to 5 min. The mechanical property of PGA scaffold after heat setting is better than without heat setting in the degradation experiment.
出处
《东华大学学报（自然科学版）》
CAS
CSCD
北大核心
2014年第1期22-27,共6页
Journal of Donghua University(Natural Science)
基金
国家八六三计划课题资助项目(2012AA020507)
