摘要
目的分析新生儿肺炎的主要病原菌及药敏情况，以指导临床合理应用抗生素。方法回顾性分析698例新生儿肺炎呼吸道分泌物细菌培养和药敏试验。结果698例新生儿肺炎呼吸道分泌物标本检出病原菌431株（其中复合菌24株），革兰阴性杆菌占60．79％，大肠埃希菌、鲍曼不动杆菌、铜绿假单胞菌为主要病原菌，对亚胺培南、头孢派酮／舒巴坦、喹诺酮类、多粘菌素敏感；革兰阳性球菌占31．09％，金黄色葡萄球菌、溶血性葡萄球菌为主要致病菌，对万古霉素、替考拉宁敏感，未发现万古霉素耐药菌株。结论革兰阴性菌是新生儿肺炎的主要病原菌，临床用药应根据药敏试验合理选择抗生索。
Objective To analyze the main pathogenic bacteria and drug sensitivity in neonatal pneumonia, and provide evidences for clinical doctor to choose reasonable antibiotics. Methods Bacte- rial culture and drug sensitivity test in 698 cases of neonatal pneumonia were analyzed retrospectively. Results Four hundred and thirty-one strains of pathogenic bacteria （ including 24 strains of compound bacteria） were isolated from the 698 specimens. Gram-negative bacilli accounting for 60.79%. Gram- positive cocci account for 31.09% , gram-negative bacteria, mainly including Escheriehia coli, bauman acinetobacter and Pseudomonas aeruginosa, were sensitive to Imipenem, cefoperazone/sulbactam, fluoro- quinolones, muhi-polymyxin meropenem. Gram-positive bacteria, mainly Staphylococcus haemolyticus and Staphylococcus aureus, were sensitive to Vancomycin and teicoplanin, but no vancomycin resistant strains were detected. Conclusions The main bacteria of neonatal pneumonia are gram-negative bacteri- a. The antibiotic should be chosen on the basis of the microbial sensitivity test.
出处
《中国实用医刊》
2014年第7期67-69,共3页
Chinese Journal of Practical Medicine
关键词
新生儿肺炎
细菌
药敏试验
抗生素
耐药性
Neonatal pneumonia
Bacteria
Drug sensitivity test
Antibiotics
Antimicrobial re-sistance
