摘要
目的探讨血清视黄醇结合蛋白(RBP)、胱抑素C(Cys C)与尿微量白蛋白(mAlb)测定在诊断原发性高血压、2型糖尿病、高血压伴糖尿病患者早期肾损伤中的临床应用价值。方法采用美国贝克曼公司AU5811全自动生化分析仪测定200例肾功能损害患者及100例正常对照血清中的RBP、Cys C、mAlb、尿素氮(BUN)、肌酐(SC r)的含量。结果肾功能损害组的RBP、Cys C、mAlb水平均高于正常对照组(P<0.01),血清尿素氮(BUN)、肌酐(SC r)水平与正常对照组比较差异无统计学意义(P>0.05)。结论 RBP、Cys C、mAlb均可作为早期肾损害的灵敏指标,三者联合检测的临床应用价值更大。
Objective To discuss the clinical application of serum retinol binding protein, Cystatin C and Urinary albumin detection in the diagnosis of early renal injury in patients with primary hypertension, Type 2 diabetes or hypertension and diabetes. Methods The contents of RBP, CysC, mAlb, BUN and SCr in 200 renal iniury patients and in 100 normal patients were detected by American Beckmann full automatic biochemical analyzer （AU5811）. Results The contents of RBP, Cys C and mAlb in the renal injury group were higher than those in the control group（ P〈0.01）, but no significant difference in the contents of BUN and SCr was found between the two groups（ P〉0.05）. Conclusion RBP, Cys C and mAlb can be used as the indexes of diagnosing early renal injury and they may produce more clinical value when in integrated detection.
出处
《山东医学高等专科学校学报》
2014年第1期58-60,共3页
Journal of Shandong Medical College
