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窄谱中波紫外线联合他克莫司软膏治疗白癜风的临床疗效观察 被引量:26

Clinical efficacy of narrow-band UVB phototherapy combined with tacrolimus ointment in the treatment of vitiligo
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摘要 目的:探讨窄谱中波紫外线联合他克莫司软膏对白癜风的治疗作用。方法:收集我院2011年至2013年门诊共90例白癜风患者,随机分为两组,每组各45例患者,分为窄谱中波紫外线联合他克莫司软膏治疗组及他克莫司软膏治疗组。随访6个月,分析两组患者治愈率,并对不同部位、不同期、不同类型白癜风的治疗情况进行比较分析。结果:窄谱中波紫外线联合他克莫司软膏对白癜风的治愈率明显高于单用他克莫司软膏组,头面部白癜风治疗有效率优于肢端部、躯干四肢部,肢端部白癜风治疗效果最差。寻常型白癜风的疗效较节段型白癜风疗效好。进展期白癜风较稳定期疗效好。结论:窄谱中波紫外线联合他克莫司软膏对白癜风具有较好的治疗作用。 Objective: To investigate the therapeutic effect of narrow-band UVB combined with tacrolimus ointment for vitiligo treament. Methods:From 2011 to 2013, 90 cases of patients with vitiligo in our hospital , were randomly divided into two groups, each group 45 patients. They were divided into narrow-band UVB phototherapy combined with tacrolimus ointment treatment group and ta-crolimus ointment treatment group.Those patients were followed-up for 6 months.Two groups' cute rate were analyzed and different parts of the different phases, different types of vitiligo treatment were compared.Results: Narrow-band UVB phototherapy combined with tacrolimus ointment for vitiligo cure rate was significantly higher than that of single use of tacrolimus ointment group, the head and face of vitiligo treatment effective rate higher than the extremities, trunk limbs acral of vitiligo treatment effect is the worst.Treat-ment effect of vitiligo vulgaris is better than segmental vitiligo. Treatment effect of Vitiligo in progress period is better than it in table period. Conclusion:narrow-band UVB phototherapy combined with tacrolimus ointment is effective for vitiligo treament.
出处 《激光杂志》 CAS CSCD 北大核心 2014年第3期58-59,共2页 Laser Journal
基金 重庆市卫生局课题(编号:2013-2-301)
关键词 白癜风 窄谱中波紫外线 他克莫司 Vitiligo NB-UVB Tacrolimus
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