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Fcγ受体基因多态性与肾脏疾病相关性研究进展

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摘要 Fcγ受体属于免疫球蛋白超家族中的一员,其中FcγRⅡA、ⅡB、ⅢA、ⅢB有多态性,并因此调节FcγR和IgG亲和力:FcγRI与IgG的亲和力最高,FcγRⅢ次之,FcRγⅡ的亲和力最低.FcγR通过与IgG结合,产生一系列生理或病理反应,它的多态性不仅影响人体的生理平衡,在一定的条件下也参与免疫介导的有关疾病.
出处 《中国实验诊断学》 2014年第3期503-505,共3页 Chinese Journal of Laboratory Diagnosis
基金 吉林省自然科学基金(201115098)
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  • 1Takai T. Roles of Fc receptors in autoimmunity[J]. Nat Rev Im- munol, 2002,2 : 580.
  • 2Glassoek, RJ. The pathogenesis of idiopathic membranous ne- phropathy: a 50-year odyssey[J]. Am J Kidney Dis, 2010,56 .. 157.
  • 3Beck LH,RG Bonegio,G Lambeau, et al. M-type phospholipase A2 receptor as target antigen in idiopathic membranous nephropa :hy[J]. N Engl J Med,2009,361:11.
  • 4MeyeSehwesinger C, S Dehde,P Klug, et al. Nephrotic syndrome md subepithelial deposits in a mouse model of immune-mediated mti-podocyteglomerulonephritis[J]. J Immunol, 2011,187 : 3218.
  • 5Mchmid H. Validation of endogenous controls for gene ex-pres- ion analysis in microdisseetedhuman renal biopsies [J]. Kidney nt,2003,64(1) :356.
  • 6Thang J J, Malekpour M, Luo WT, et al. Murine Membranous Ne- )hropathy:Immunization with a3(IV) Collagen Fragment Induces ubepithelial Immune Complexes and FcgR-Independent Nephrot- c Syndrome[J]. J Immunol, 2012,7 : 3268.
  • 7Mezzamo S,Rojas G,Ardiles L,et al. Idiopathic membra/mus ne- phropathy ASSOCIATED WITH HLA-DRw3 and not related to monocytephagocyte systemic Fc recepter dysfun-ction in fa- ther and son[J]. Nephron, 1991,58 : 320.
  • 8EIshihabi I, Kaye CI, Brzowski A. Membranous nephrophthy in two human leukocyte antigen-identical brothers[J]. J Pediatr, 1993,123:940.
  • 9Clynes R, Ravetch JV. Cytotoxic antibodies trigger inflammation through Fc receptors[J]. Immunity, 1995,3 : 21.
  • 10Amigorena S, Bonnerot C, Drake JR, et al. Cytoplasmic domainheterogeneity and functions of IgG Fc receptors in B lympho cytes[J]. Science, 1992,256 : 1808.

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