摘要
视神经脊髓炎(NMO)是常见的中枢神经系统自身免疫性疾病,主要累及视神经和脊髓。自水通道蛋白4抗体发现以来,越来越多的证据提示NMO为一种独立疾病,且多数证据已纳入目前国际上常用的诊断标准。近年来还提出了NMO谱系疾病的概念,拓展了此类疾病的诊断范围。该文就NMO的流行病学、临床表现、影像学特征、免疫病理特征及治疗的研究进展进行综述,为NMO的临床诊断及治疗奠定一定的基础。
Neuromyelitis optica （NMO） is an common autoimmune disease of central nervous system involving the optic nerves and spine. Since serum anti - aquaporin - 4 antibody was found, more and more ev- idences suggest that NMO is an independent disease. And Most of the cvidenceshave been incorporated in currently used international diagnostic criteria. In recent years, the concept of NMO spectrum disorders was proposed which expands the scope of the diagnosis of these diseases. Here is to make a review of the research progress of epidemiology, clinical manifestations, imaging features, immune pathological features and treatment of NMO in order to establish foundation for the clinical diagnosis and treatment of NMO.
出处
《医学综述》
2014年第5期884-887,共4页
Medical Recapitulate
关键词
视神经脊髓炎
多发性硬化
诊断
鉴别
Neuromyelitis optica
Multiple sclerosis
Diagnosis
Differentiation
