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妊娠期血糖变化与糖化血红蛋白检测的相关性研究 被引量:3

Relevance research on gestational diabetes mellitus and glycated hemoglobin
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摘要 目的研究妊娠妇女糖化血红蛋白测定与妊娠糖尿病的相关性。方法选择正常孕妇230例作为对照组,选择妊娠并高血糖妇女150例作为实验组,比较两者空腹血糖与AbA1c变化的相关性。结果对照组空腹血糖为(4.5±0.31),实验组空腹血糖为(5.51±0.41),对照组AbA1c为(5.62±0.14),实验组AbA1c为(6.51±0.23)。实验组AbA1c显著高于对照组(P<0.05),空腹血糖高于对照组(P<0.05),相关性分析表明AbA1c与妊娠期糖尿病无相关关系,r=0.3151,P<0.05。结论糖化血红蛋白用于非妊娠期糖尿病的筛查有一定的临床意义,但妊娠期糖尿病AbA1c与空腹血糖无相关关系,r=0.3151,P>0.05。 Objective To investigate the relevance between HbA1c and gestational diabetes. Methods 230 cases of normal pregnant women( control group) and 150 cases of pregnancy women complicated with hyperglycemia( experimental group) were enrolled in this study,test and compare the concentration of fasting blood-glucose and HbA1c of the two groups. Results The concentration of fasting blood glucose of control group and experimental group were 4. 5 ± 0. 31 and 5. 51 ± 0. 41 respectively. And the levels HbA1c in the two groups were 5. 62 ± 0. 14 and 6. 51 ± 0. 23 respectively. Both the concentration of fasting blood glucose and HbA1c in experimental group were higher than those in control group( P 0. 05). There was no correlation between HbA1c and fasting blood glucose( r = 0. 3151,P 0. 05). Conclusions HbA1c test was helpful for screening gestational diabetes to a certain extent,but present no relationship with fasting blood glucose.
作者 望丹丹 王丽
出处 《齐齐哈尔医学院学报》 2014年第3期357-358,共2页 Journal of Qiqihar Medical University
关键词 妊娠 血糖 糖化血红蛋白 糖尿病 Pregnancy Fasting blood glucose AbA1c Diabetes
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参考文献3

  • 1Ibrahim H,Ismail AH,Ismail SB,et al.The use of AbA1c in the diagnosis of diabetes mellitus type 2 inhigh risk subjects[J] ,Int J Diabetes Metab,2010,18(1):25-26.
  • 2Bennett CM,Guo M,Dharmage SC.HbA1c as a screening tool fordetection of type 2 diabetes:a systematic review[J] ,Diabet Med,2007,24(4):333-335.
  • 3中华人民共和国国家药典委员会.中华人民共和国药典一部[S] .北京,工业化学出版社,2005:3-19.

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