摘要
目的:分析卵巢恶性甲状腺肿(MSO)的临床病理特点。方法:收集5例MSO的临床资料对其进行病理组织学观察和免疫组织化学标记并复习相关文献。结果:5例MSO均表现为盆腔包块,无临床恶性及转移证据,形态学上常伴有畸胎瘤成分或可见甲状腺病变良性到恶性的移行过程,免疫组化TTF-1、TG阳性。结论:MSO是少见肿瘤,缺少特异临床症状,病理组织学诊断标准同甲状腺原发恶性病变,可为畸胎瘤的一部分。组织学可分为乳头型和滤泡型,总体预后好。
Objective: To analyze the clinical pathological features of malignant struma ovarii (MSO). Methods:The clinical data, histological and finding of 5 cases of MSO was researched with review of literature. Results: Pelvic mass was showed in all the 5 cases, without any clinical evidence of malignancy or metastasis. Morphologically, MSO was found to arrise from teratoma, sometime with transition from benign to malignant, immunohistochemistry showed TTF-1 and TG positive. Conclusion: As a rare tumor, MSO, whose histopathological diagnostic criteria is similar to that of the thyroid primary malignant lesion, is lack of specific clinical symptoms and may be constituent of teratoma. It is divided into papillary and follicular types in histology. It has a good prognosis.
出处
《温州医学院学报》
CAS
2014年第2期141-144,共4页
Journal of Wenzhou Medical College
关键词
卵巢畸胎瘤
恶性甲状腺肿
癌
乳头状
ovarian teratoma
malignant struma ovarii
carcinoma, papillary