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HCV抗体ELISA检测假阳性分析 被引量:4

Analysis of false positive detection of HCV antibody by ELISA
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摘要 目的:探讨HCV抗体ELISA检测1<S/CO均值<3.8时假阳性问题。方法筛选HCV抗体ELISA首次检测1<S/CO(3次均值)<3.8共26例,正常体检人群20例,2~6月之间再次抽血检测。结果26例首次检测ELISA有反应性其中6例再次检测为阴性,最终该6例患者确诊为阴性,20例正常体检人群2次均为阴性。两次检测比较结果有显著性差异(P<0.01)。结论 HCV抗体ELISA检测有反应性时应定期复查或做其它检测。 Objective To discuss the false positive problem when the S/CO mean of HCV Ab test by ELISA is between 1 to 3.8. Methods 26 cases whose first S/CO mean(3 times by ELISA) was between 1 to 3.8 and 20 cases of normal healthy people were chosen. Do blood test again from 2 months to 6 months. Results 6 cases among 26 cases of reactive result of first ELISA tested negative in the second experiment.20 normal individuals tested negative twice by ELISA.There is significance difference between two test(P〈0.01). Conclusion If detection of HCV Ab by ELISA is reactive,should be regularly reviewed,or do other tests.
作者 张力 张文娟
出处 《中国医药科学》 2014年第3期114-116,130,共4页 China Medicine And Pharmacy
关键词 丙型肝炎病毒 抗体 酶联免疫法 HCV Ab ELISA
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