摘要
Irisin是一种新发现的由骨骼肌分泌的因子.最新研究证实,Irisin是联系骨骼肌和其他组织的桥梁,对能量的稳态及代谢平衡起重要作用.Irisin可以促进白色脂肪组织棕色化,增加能量消耗,改善胰岛素抵抗.实验证明多种与能量代谢有关的因素,如运动、体重指数等,都可以影响受试者血清Irisin的水平.推测Irisin将可能成为代谢性疾病,尤其是与运动相关的代谢性疾病治疗的新方向.
Irisin is a newly discovered cytokine secreted by skeletal muscle.Latest studies have confirmed that Irisin is a bridge regarding the interactions between skeletal muscle and other tissues,and plays an important role in energy homeostasis and metabolic balance.Irisin can contribute to the brown-fat-like conversion of white adipose tissues,increase energy consumption,and ameliorate insulin resistance.Many experiments have verified that many factors related to energy metabolism,such as exercise and body mass index,can affect serum Irisin.It suggests that Irisin might become a new target for treatment of metabolic disease,especially the diseases related to exercise.
出处
《国际内分泌代谢杂志》
北大核心
2014年第2期109-111,共3页
International Journal of Endocrinology and Metabolism
基金
国家自然科学基金资助项目（30700387）
关键词
体重指数
运动
2型糖尿病
Irisin
Irisin
Body mass index
High-fat diet
Exercise
Type 2 diabetes mellitus
