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血B型尿钠肽前体(NT-proBNP)在急诊老年COPD合并心衰患者中的临床意义探讨 被引量:8

Exploration of clinical significance of NT-proBNP in the emergency treatment of senile patients with chronic obstructive pulmonary disease complicated with heart failure
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摘要 目的 探讨急诊COPD合并心衰患者检测NT-proBNP的临床意义.方法 选取我院2010年3月~2012年10月收治的98例COPD患者作为研究对象,选取单纯COPD患者50例患者作为对照组,COPD合并心衰患者48例作为观察组,比较NT-proBNP水平组间差异及治疗前后差异.结果 两组患者NT-proBNP及LVEF、LVFS水平比较均有显著差异(P〈0.01),治疗后观察组NT-proBNP水平与对照组比较仍有显著差异(P〈0.01),不同心功能分级患者NT-proBNP水平比较有显著差异(P〈0.01).结论 急诊可应用NT-proBNP检测作为判断COPD是否合并心衰的可靠指标. Objective To investigate the clinical significance of NT-proBNP in the emergency treatment of senile patients with chronic obstructive pulmonary disease complicated with heart failure. Methods 98 COPD patients were selected as the research group, including 50 cases of patients with COPD only as the control group and 48 COPD patients complicated with heart failure as the observation group. The level of NT-proBNP was detected before and after the treatment between the two groups. Results There were significant differences in NT-proBNP and LVEF between the two groups before the treatment (P〈0.01). After the treatment, there still existed significant difference in NT-proBNP between the two groups (P〈0.01). Conclusion NT-proBNP can be used as a reliable index to determine whether COPD patients are complicated with heart failure.
作者 侯士云
出处 《临床肺科杂志》 2014年第4期630-632,共3页 Journal of Clinical Pulmonary Medicine
关键词 血B型尿钠肽前体 慢性阻塞性肺疾病 心力衰竭 意义 serum B type natriuretic peptide precursor chronic obstructive pulmonary disease heart failure significance
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