摘要
目的观察中西医结合治疗难治性消化性溃疡愈合质量的临床疗效。方法将100例难治性消化性溃疡患者,随机分为2组。对照组50例给予西药兰索拉唑治疗,治疗组在对照组基础上加用健胃消炎颗粒治疗。治疗3个月后统计2组的临床疗效、溃疡愈合质量、幽门螺杆菌(Hp)根除效果及复发情况。结果治疗组总有效率96.0%,对照组82.0%,治疗组疗效优于对照组(P<0.05)。胃镜下溃疡愈合情况及溃疡愈合质量,治疗组优于对照组,差异有统计学意义(P<0.05)。2组治疗后Hp根除率比较差异有统计学意义(P<0.05)。停药后6个月、9个月2组复发率比较差异有统计学意义(P<0.05),治疗组明显低于对照组。结论采用中西医结合治疗难治消化性溃疡,能减轻患者的临床症状,促进溃疡愈合,提高溃疡愈合质量,降低复发率,疗效确切。
Objective To study clinical effect of integrated traditional Chinese and western medicine in treatment of refractory peptic ulcer. Methods 100 patients diagnosed refractory peptic ulcer were divided into two groups randomly. 50 cases in control group were treated by lansoprazole. Treatment group received Jianwei Xiaoyan granule on the basis of control group treatment. The clinical effect, healing condition and quality, HP eradication rate and recurrence were analyzed after three months of treatment. Result The total effective rate of experiment group was 96.0%, that of control group was 82.0%, there were statistical difference between two groups （ P 〈 0.05 ）. The ulcer healing condition and ulcer healing quality under gastroscope in experiment group were better than that in control group （P 〈 0.05）. The HP eradication rate of experiment group were better than control group, there were statistical difference （ P 〈 0.05 ）. The recurrence rate in experiment group was lower than that in control group after six and nine months of withdrawal （ P 〈 0.05 ）. Conclusion Integrated traditional Chinese and western medicine in treatment of refractory peptic ulcer was good at to alleviate clinical symptoms, promote healing condition and quality. And the clin- ical effect was affirmative and significant.
出处
《河北中医》
2014年第3期379-382,共4页
Hebei Journal of Traditional Chinese Medicine
关键词
消化性溃疡
螺杆菌
幽门
中西医结合疗法
Peptic ulcer
Helicobaeter
Pylori
Integrated traditional Chinese and western medicine
