摘要
目的:为了解肝病患者的免疫功能状态。方法:对慢性肝炎、肝硬化和原发性肝癌患者进行红细胞免疫、T细胞亚群及自然杀伤细胞活性进行检测。结果:每一组的红细胞C3b受体花环率、红细胞免疫粘附促进因子、CD3+细胞、CD4+细胞、CD4+/CD8+细胞比值和自然杀伤细胞活性均明显低于对照组。肝癌组较其它组降低更明显。但各组的红细胞免疫复合物花环率、红细胞免疫粘附促进因子和CD8+细胞均明显高于对照组。肝癌组还明显高于慢肝组。结论:肝病患者免疫功能严重受损,监测以上免疫指标,对判断预后。
Objective:To probe into immunity function of hepatopath Method:[WT5,5”BZ]Red blood cell (RBC) immunity,T cell subset and natural killer (NK) cell activity were tested in patients with chronic hepatitis (CH) liver cirrhosis (LC) and primary hepatic carcinoma (PHC) Results:[WT5,5”BZ]The result showed that the percentage of RBC C 3b receptor rosette (RBC CD 3bRR),RBC immunity adherence enhance ment factor (RFER),CD 3 + cell CD 4 + cell,ratio of CD 4 +/CD 8 + and NK cell activity in every group were significantly decreased compared with control group,and those in PHC group were fewer than those in other groups But the percentage of RBC IC rosette (RBC ICR),RBC immunity adherence inhibitor factor (RFIR) and CD 8 + cell in any group were higher significantly than those in controls,and those in PHC group were higher than those in CH group Conclusion:[WT5,5”BZ]The study indicates that the immunity function was seriously impaired in hepatopath To monitor the immunity index above may serve as a guide for the assessment of prognosis and the choice of rational therapy
出处
《广西医科大学学报》
CAS
1999年第6期795-796,共2页
Journal of Guangxi Medical University
